| 8:00 am - 7:00 pm |
Thursday, July 14th, Symposium Sessions 5-8 (on Zoom #1): |
| 8:00 am - 9:00 am |
Breakfast, Science Commons Atrium |
| 9:00 am - 10:30 am |
Session 5 - Chair: Olwyn Byron, University of Glasgow |
Beadmodeling, SAXS/SANS and hydrodynamic simulations |
| 9:00 am - 10:00 am |
Svedberg Keynote Lecture: Jose Garcia de la Torre, Universidad de Murcia (remote) |
50 years with beads and springs. A self-review of some contributions and a few new projects |
| 10:00 am - 10:30 am |
Mattia Rocco, Ospedale Policlinico San Martino |
US-SOMO-AF: a database of hydrodynamic, circular dichroism, and SAXS-derived parameters for the AlphaFold-predicted protein structures
Lecture slides
|
| 10:30 am - 10:50 am |
Coffee Break |
| 10:50 am - 12:20 am |
Session 6 - Chair: Walter Stafford, Harvard University |
High Concentration and Non-ideality |
| 10:50 am - 11:20 am |
Jack Correia, University of Mississippi |
Sedimentation Velocity Studies of Pooled Human Serum |
| 11:20 am - 11:50 am |
Alexander Yarawsky, Cincinnati Childrens Hospital Medical Center |
Strong nonideality effects at low protein concentrations: considerations for elongated proteins |
| 11:50 am - 12:20 pm |
Tom Laue, University of New Hampshire (remote) |
B22measured/B22max provides a rigorous means to select for high protein solubility and low viscosity |
| 12:20 pm - 1:30 pm |
Lunch Break |
| 1:30 pm - 3:00 pm |
Session 7 - Chair: Karen Fleming, Johns Hopkins University |
Protein Applications for AUC |
| 1:30 pm - 2:00 pm |
Todd Stone, Catalent |
AUC in Pharmaceutical Product Development - A New Spin with an "Old" Instrument |
| 2:00 pm - 2:30 pm |
Taylor Devlin, Johns Hopkins University |
Observing chaperone-client interactions by sedimentation velocity analytical ultracentrifugation |
| 2:30 pm - 3:00 pm |
Christine Ebel, Institut de Biologie Structurale |
Structure and Motion of Membrane Proteins as Seen by SANS |
| 3:00 pm - 3:20 pm |
Coffee Break |
| 3:20 pm - 4:50 pm |
Session 8 - Chair: Ute Curth, Hannover Medical School |
Nucleic Acid Applications for AUC |
| 3:20 pm - 3:50 pm |
Higor Pereira, University of Lethbridge |
Nucleolin Interacts with Short-hairpin/3’stem-loop in Flavivirus 3’ Terminal Region |
| 3:50 pm - 4:20 pm |
Maduni Ranasinghe, University of Lethbridge |
Biophysical characterization of DNA minicircle topoisomers to derive anisotropy and partial specific volume using a global analysis of analytical ultracentrifugation data |
| 4:20 pm - 4:50 pm |
Borries Demeler, University of Lethbridge |
Density Matching Multi-Wavelength Analytical Ultracentrifugation to Measure Drug Loading of Lipid Nanoparticle Formulations |
| 4:50 pm - 6:00 pm |
Break |
| 6:00 pm - 7:30 pm |
Dinner |
| 7:30 pm |
Dukes Pub & Grill/Free Time |
